British Air Force Typhoon fighter aircraft have operated alongside France's air force in a combined operation against an subterranean weapons facility in Syrian territory used by the IS group, as stated by the UK's MoD.
The facility, pinpointed through reconnaissance, was thought to be containing munitions and bombs, the announcement noted, and was situated in hills just north of the ancient city of Palmyra in central Syria.
"Our fighter planes utilized precision-guided Paveway IV munitions to target a series of access tunnels down to the depot... preliminary assessments are that the strike was effective," the ministry announced.
There was no indication of any civilian casualties in the strike conducted Saturday night and all the aircraft returned to base without incident, the MoD added.
The British jets were backed up by a Voyager tanker plane.
The Islamic State group - also known as Daesh - enforced jihadist rule over significant areas in both Syria and Iraq until 2019.
"This strike demonstrates the UK's leading role, and determination to stand shoulder to shoulder with allied nations, to eliminate any resurgence of Daesh and their violent and radical beliefs in the area," the British Defence Secretary the Defence Secretary remarked.
UK warplanes have conducted surveillance missions over Syria to "prevent any attempted comeback" of IS after its military defeat at the battle of Baghuz in the year 2019, the MoD reported.
"I must thank all the members of our armed forces who took part in this strike for their skill and their courage," he commented. "Including them were numerous UK service members on duty over the festive period. This mission, to eliminate terrorist threats who endanger our safety, demonstrates how British military are ready to step up, throughout the year, keeping Britain secure within its borders and strong abroad."
During December, the US military carried out what it termed a "large-scale strike" targeting IS targets in the country, after an ambush resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The UN reports Islamic State still maintains between 5,000 and 7,000 fighters in both countries.